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آنچه در انتظارش بودیم - یک رویای در حال تحقق: رشد مجدد دندان ها با دارو
𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭𝐬 𝐨𝐧 𝐭𝐡𝐞 𝐕𝐞𝐫𝐠𝐞 𝐨𝐟 𝐑𝐞𝐯𝐨𝐥𝐮𝐭𝐢𝐨𝐧𝐚𝐫𝐲 𝐃𝐞𝐧𝐭𝐚𝐥 𝐑𝐞𝐠𝐞𝐧𝐞𝐫𝐚𝐭𝐢𝐨𝐧 𝐒𝐨𝐥𝐮𝐭𝐢𝐨𝐧
The first human tooth regrowth pharmaceutical is poised to commence clinical trials involving human subjects within the upcoming months, potentially as early as September of this year. Should these trials prove successful, it is anticipated that the drug will be made commercially available to the general public prior to the year 2030.
The drug, developed by a team of Japanese researchers, will undergo its initial clinical phase, spanning 11 months, involving a cohort of children aged 2 to 7 years with congenital agenesis of four permanent teeth. Subsequently, the trial will progress to a phase involving individuals who have lost 1 to 5 teeth due to environmental factors.
This groundbreaking pharmaceutical innovation operates by effectively neutralizing the activity of a specific protein gene known as USAG-1. This protein engages in interactions with other proteins, thereby impeding the natural process of tooth development. Through the targeted inhibition of USAG-1, a pathway is effectively established, facilitating the remarkable regrowth of teeth.
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